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Mivacurium dichloride

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Chemical Structure| 106861-44-3 同义名 : 米库氯铵 ;Mivacurium (chloride)
CAS号 : 106861-44-3
货号 : A294438
分子式 : C58H80Cl2N2O14
纯度 : 98%
分子量 : 1100.167
MDL号 : MFCD00867767
存储条件:

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 250 mg/mL(227.24 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 100 mg/mL(90.9 mM)

动物实验配方:
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

0.91mL

0.18mL

0.09mL

4.54mL

0.91mL

0.45mL

9.09mL

1.82mL

0.91mL

参考文献

[1]Delu Che, et al. Mivacurium Induce Mast Cell Activation and Pseudo-Allergic Reactions via MAS-related G Protein Coupled receptor-X2. Cell Immunol. 2018 Oct;332:121-128.

[2]Matthias Paul, et al. The Potency of New Muscle Relaxants on Recombinant Muscle-Type Acetylcholine Receptors. Anesth Analg. 2002 Mar;94(3):597-603; table of contents.

[3]J E Caldwell. New Skeletal Muscle Relaxants. Int Anesthesiol Clin. Winter 1995;33(1):39-60.