生物活性 | |||
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描述 | MI-2, a MALT1 inhibitor (IC50=5.84 μM), directly targets MALT1, irreversibly inhibiting its protease activity. This inhibition is associated with decreased NF-κB reporter activity, blocked c-REL nuclear translocation, and reduced expression of NF-κB-dependent genes. MI-2 is non-toxic to animals[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.19mL 0.44mL 0.22mL |
10.97mL 2.19mL 1.10mL |
21.94mL 4.39mL 2.19mL |
参考文献 |
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