Dihydroethidium
产品说明书
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同义名 : | Hydroethidine;PD-MY 003;HE;DHE |
| CAS号 : | 104821-25-2 | |
| 货号 : | A286650 | |
| 分子式 : | C21H21N3 | |
| 纯度 : | 98%+ | |
| 分子量 : | 315.411 | |
| MDL号 : | MFCD00077335 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,Store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(158.52 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dihydroethidium (DHE) is a peroxide indicator that readily penetrates cell membranes and forms a fluorescent protein complex. It predominantly accumulates in the cell membrane, cytoplasm, and nucleus, with the most intense staining observed in the nucleus. Dihydroethidium naturally emits blue fluorescence, with a peak excitation wavelength at 370 nm and emission at 420 nm. Upon dehydrogenation, it binds to RNA or DNA to produce red fluorescence, peaking at 300 nm for excitation and 610 nm for emission. An excitation wavelength of 535 nm is also applicable for practical observation[1]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02361944 | Cardiac Surgery | Not Applicable | Recruiting | December 2020 | United States, Tennessee ... 展开 >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37212 Contact: Frederic T. Billings, IV, MD, MSc 615-343-6479 frederic.t.billings@vanderbilt.edu 收起 << |
| NCT02758431 | Hypogonadism | Not Applicable | Recruiting | January 2021 | United States, Colorado ... 展开 >> University of Colorado CCTSI CTRC Recruiting Denver, Colorado, United States, 80045 Contact: Kerrie Moreau, PhD 303-724-1914 kerrie.moreau@ucdenver.edu 收起 << |
| NCT02862886 | Pregnancy | Not Applicable | Completed | - | France ... 展开 >> CHU Dijon Bourgogne Dijon, France, 21079 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.17mL 0.63mL 0.32mL |
15.85mL 3.17mL 1.59mL |
31.70mL 6.34mL 3.17mL |
| 参考文献 |
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