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Isoacteoside

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Chemical Structure| 61303-13-7 同义名 : 异麦角甾苷 ;Isoverbascoside
CAS号 : 61303-13-7
货号 : A276968
分子式 : C29H36O15
纯度 : 99%+
分子量 : 624.587
MDL号 : MFCD06798947
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(400.26 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Isoacteoside is a natural compound isolated and purified from the herb of Pedicularis striata Pall. which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls, and exhibits anti-inflammatory effects through blocking TLR4 dimerization.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.60mL

0.32mL

0.16mL

8.01mL

1.60mL

0.80mL

16.01mL

3.20mL

1.60mL
参考文献

[1]Nam SY, Kim HY, et al. Anti-inflammatory effects of isoacteoside from Abeliophyllum distichum. Immunopharmacol Immunotoxicol. 2015 Jun;37(3):258-64.

[2]Yu SY, Lee IS, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79(18):1705-9.