Muscone

产品说明书

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Chemical Structure| 541-91-3 同义名 : 3-甲基环十五烷酮 ;3-Methylcyclopentadecanone;Methylexaltone
CAS号 : 541-91-3
货号 : A275816
分子式 : C16H30O
纯度 : 97%
分子量 : 238.409
MDL号 : MFCD00211114
存储条件:

Pure form Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(440.42 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Muscone, a natural product isolated and purified from Mosochus Bersxoxskii Fleror, could permeate the BBB model, and it was associated with the inhibition of P-gp and MMP-9 expression, is the important mechanisms for treating cerebral vascular diseases.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.19mL

0.84mL

0.42mL

20.97mL

4.19mL

2.10mL

41.94mL

8.39mL

4.19mL

参考文献

[1]Chen ZZ, Lu Y, et al. Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model. Int J Pharm. 2013 Nov 1;456(1):73-9.

[2]Wei G, Chen DF, et al. Muscone exerts neuroprotection in an experimental model of stroke via inhibition of the fas pathway. Nat Prod Commun. 2012 Aug;7(8):1069-74.