Cesium chloride
产品说明书
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同义名 : | 氯化铯 |
| CAS号 : | 7647-17-8 | |
| 货号 : | A270389 | |
| 分子式 : | ClCs | |
| 纯度 : | 99% | |
| 分子量 : | 168.358 | |
| MDL号 : | MFCD00010955 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,Room temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
H2O: 100 mg/mL(593.97 mM) |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Cesium chloride is a blocker of potassium channel. Cesium Chloride (12 mg/100 g body weight, daily for 30 days; i.p.; male Wistar rats- BOO model) could significantly weaken the effect of XJT (traditional Chinese medicine) on not only the expression of these potassium channels but also the bladder weight, urodynamics, and oxidative stress[2]. Cesium chloride has primarily been used in cardiovascular research for arrhythmogenesis in animals because of its potassium-blocking effects[3]. In animal models, cesium chloride has induced cardiac arrhythmias, including torsade de pointes. It inhibits delayed rectifier potassium channels in the myocardium, causing delayed repolarization and QT-interval prolongation[4]. The number of the cells was decreased by application of 1-10 mM cesium in a dose-dependent manner, whereas the viability of the cells was unchanged. Cesium inhibits the proliferation and migration of fibroblast cells[5]. Cesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein[6]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
5.94mL 1.19mL 0.59mL |
29.70mL 5.94mL 2.97mL |
59.40mL 11.88mL 5.94mL |
| 参考文献 |
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