α-L-Rhamnose monohydrate
产品说明书
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同义名 : | L-鼠李糖单水合物 ;6-deoxy-L-mannose monohydrate;α-L-Rhamnopyranose monohydrate |
| CAS号 : | 6155-35-7 | |
| 货号 : | A269967 | |
| 分子式 : | C6H14O6 | |
| 纯度 : | 98% | |
| 分子量 : | 182.172 | |
| MDL号 : | MFCD00071591 | |
| 存储条件： |
Pure form Sealed in dry,Room Temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(576.38 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(548.93 mM) |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | L-Rhamnose monohydrate (Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies[3]. Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption[4]. The main monosaccharides found in RHWPs were mannose, ribose, l-rhamnose monohydrate, glucuronic acid, galacturonic acid, glucose, galactose, xylose, arabinose, and fucose. RHWPs inhibited the proliferation of S180 tumor cells and induced apoptosis in vitro. Oral administration of RHWPs to tumor-bearing mice significantly inhibited the growth of the S180 xenografts, accelerated apoptosis in tumor cells, and expanded the necrotic regions. Furthermore, RHWPs also markedly increased the levels of TNF-α, IFN-γ, and IL-2 in the sera of tumor-bearing mice, and activated immune cells such as lymphocytes, NK cells, and macrophages, thereby inducing tumor cell apoptosis[5]. L-rhamnose treatment in 3T3-L1 adipocytes also significantly elevated protein levels of p-HSL, p-AMPK, ACOX, and CPT1 as well as reduced levels of ACC, FAS, C/EBPα, and PPARγ, suggesting its possible role in enhancement of lipolysis and lipid catabolism as well as reduced adipogenesis and lipogenesis, respectively[6]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
5.49mL 1.10mL 0.55mL |
27.45mL 5.49mL 2.74mL |
54.89mL 10.98mL 5.49mL |
| 参考文献 |
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