产品说明书

KBU2046

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Chemical Structure| 1143863-69-7 同义名 : -
CAS号 : 1143863-69-7
货号 : A267882
分子式 : C15H11FO2
纯度 : 97%
分子量 : 242.245
MDL号 : MFCD28970009
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(206.4 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 KBU2046 is an orally active, highly selective inhibitor of cell motility and cell invasion in vitro. KBU2046 binds to chaperone heterodimeric complexes, selectively alters binding of client proteins that regulate cell motility and does not possess all of the characteristics of classical HSP90 inhibitors. KBU2046 inhibits cancer metastasis and prolongs life[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.13mL

0.83mL

0.41mL

20.64mL

4.13mL

2.06mL

41.28mL

8.26mL

4.13mL

参考文献

[1]Xu L, et al. Precision therapeutic targeting of human cancer cell motility. Nat Commun. 2018 Jun 22;9(1):2454.