产品说明书
Ciprofloxacin hydrochloride monohydrate
 |
同义名 : | 环丙沙星盐酸盐一水合物 ;Bay-09867 hydrochloride monohydrate;Ciprofloxacin hydrochloride hydrate;Ciprofloxacin HCl monohydrate |
| CAS号 : | 86393-32-0 | |
| 货号 : | A267840 | |
| 分子式 : | C17H21ClFN3O4 | |
| 纯度 : | 98% | |
| 分子量 : | 385.818 | |
| MDL号 : | MFCD00242856 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 4 mg/mL(10.37 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ciprofloxacin (Bay-09867) hydrochloride monohydrate, a robust orally active topoisomerase IV inhibitor, induces damage to mitochondrial and nuclear DNA, resulting in mitochondrial dysfunction and ROS production. It exhibits anti-proliferative effects and promotes apoptosis, and is recognized as a potent fluoroquinolone antibiotic with substantial antibacterial properties[1].[2].[3].[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.59mL 0.52mL 0.26mL |
12.96mL 2.59mL 1.30mL |
25.92mL 5.18mL 2.59mL |
| 参考文献 |
|---|