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Siamenoside I

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Chemical Structure| 126105-12-2 同义名 : 翅子罗汉果 I
CAS号 : 126105-12-2
货号 : A267025
分子式 : C54H92O24
纯度 : 98%
分子量 : 1125.294
MDL号 : MFCD12546129
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(93.31 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(44.43 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Mogrosides are responsible for the sweet taste and bioactivities of Siraitiae Fructus (Luo Han Guo in Chinese, the ripe fruits of Siraitia grosvenorii), a traditional Chinese medicine and an edible fruit. Siamenoside I is the sweetest mogroside that has several kinds of bioactivities. In rats, the metabolic reactions of siamenoside I include deglycosylation, hydroxylation, dehydrogenation, deoxygenation, isomerization, and glycosylation, among which the deglycosylation and oxidation (hydroxylation, dehydrogenation) are the major metabolic reactions of siamenoside I. In total, 86 new metabolites of siamenoside I were detected in different biological samples from rats. Eight metabolites (M3, mogroside IVA; M4, mogroside IVE; M8, mogroside III; M15, mogroside IIE; M24, mogroside IA1; M25, mogroside IE1; M29, mogrol; M9, mogroside IIIE) of siamenoside I can be regarded as bioactive metabolites. The distributions of siamenoside I and its 86 metabolites in rat organs were firstly reported, and they were mainly distributed to intestines, the stomach, kidneys, and the brain[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

0.89mL

0.18mL

0.09mL

4.44mL

0.89mL

0.44mL

8.89mL

1.78mL

0.89mL
参考文献

[1]Yang XR, Xu F, et al. Metabolites of Siamenoside I and Their Distributions in Rats. Molecules. 2016 Jan 30;21(2):176.

[2]Metabolites of Siamenoside I and Their Distributions in Rats