产品说明书
Benzylacetone
 |
同义名 : | 4-苯基-2-丁酮 ;4-Penylbutan-2-one;Methyl 2-phenylethyl ketone;4-Phenyl-2-butanone |
| CAS号 : | 2550-26-7 | |
| 货号 : | A265752 | |
| 分子式 : | C10H12O | |
| 纯度 : | 98% | |
| 分子量 : | 148.202 | |
| MDL号 : | MFCD00008790 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(708.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity, with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively. Tyrosinase (EC 1.14.18.1) is the key enzyme of melanin synthesis and fruit-vegetable browning[1]. Benzylacetone is released by heated agarwood, when inhaled it has a potent effect on reducing the locomotor activity of mice. Benzylacetone-like compounds had sedative activities and their intensities varied depending on the functional group in the carbon chain, the substituent in the benzene ring, and their combinations[2]. Benzylacetone has appetite-enhancing and locomotor-reducing effects. The effective doses for these two outcomes overlap, and the weight gain of mice exposed to benzylacetone is caused by both appetite-enhancement and a reduction in locomotor activity[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.75mL 1.35mL 0.67mL |
33.74mL 6.75mL 3.37mL |
67.48mL 13.50mL 6.75mL |
| 参考文献 |
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