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ERK5-IN-5

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Chemical Structure| 2318792-30-0 同义名 : -
CAS号 : 2318792-30-0
货号 : A2626759
分子式 : C19H16ClN3O
纯度 : 98%
分子量 : 337.803
MDL号 : N/A
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(310.83 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 ERK5-IN-5, as an ERK5 kinase suppressor, demonstrates anticancer properties by showing potent anti-proliferative effects with an IC50 of 6.23 µg/mL against A549 cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.96mL

0.59mL

0.30mL

14.80mL

2.96mL

1.48mL

29.60mL

5.92mL

2.96mL
参考文献

[1]Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.