产品说明书

Tildipirosin

Print
Chemical Structure| 328898-40-4 同义名 : -
CAS号 : 328898-40-4
货号 : A262611
分子式 : C41H71N3O8
纯度 : 99%+
分子量 : 734.018
MDL号 : MFCD13194925
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(143.05 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Tildipirosin is a 16-membered macrolide for treatment, control, and prevention of bovine respiratory disease by inhibiting protein synthesis on the ribosome (IC50= 0.23 ± 0.01 μM).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.36mL

0.27mL

0.14mL

6.81mL

1.36mL

0.68mL

13.62mL

2.72mL

1.36mL
参考文献

[1]Rose M, Pridmore A, et al. A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. J Vet Pharmacol Ther. 2016 Jun;39(3):277-86.

[2]Angell JW, Clegg SR, et al. In vitro susceptibility of contagious ovine digital dermatitis associated Treponema spp. isolates to antimicrobial agents in the UK. Vet Dermatol. 2015 Dec;26(6):484-7, e114-5.