产品说明书

Polygalaxanthone III

Print
Chemical Structure| 162857-78-5 同义名 : -
CAS号 : 162857-78-5
货号 : A252947
分子式 : C25H28O15
纯度 : 99%
分子量 : 568.481
MDL号 : MFCD23704367
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(439.77 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Polygalaxanthone III, a natural product isolated and purified from the roots of Polygala tenuifolia Willd., can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.76mL

0.35mL

0.18mL

8.80mL

1.76mL

0.88mL

17.59mL

3.52mL

1.76mL
参考文献

[1]Lv C, Li Q, et al. Simultaneous quantitation of polygalaxanthone III and four ginsenosides by ultra-fast liquid chromatography with tandem mass spectrometry in rat and beagle dog plasma after oral administration of Kai-Xin-San: application to a comparative pharmacokinetic study. J Sep Sci. 2014 May;37(9-10):1103-10.

[2]Lv C, Li Q, et al. A UFLC-MS/MS method with a switching ionization mode for simultaneous quantitation of polygalaxanthone III, four ginsenosides and tumulosic acid in rat plasma: application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats. J Mass Spectrom. 2013 Aug;48(8):904-13.