产品说明书

Silver Sulfadiazine

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Chemical Structure| 22199-08-2 同义名 : AgSD
CAS号 : 22199-08-2
货号 : A250558
分子式 : C10H9AgN4O2S
纯度 : 97%
分子量 : 357.137
MDL号 : MFCD00072101
存储条件：

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Silver sulfadiazine (AgSD) exerts a dual inhibitory effect on bacterial growth. Its sulfonamide component inhibits bacterial folate absorption and DNA synthesis, while the released silver binds to and disrupts bacterial DNA, hindering DNA replication[1]. AgSD is widely used as a topical antibiotic for studying bacterial infections in burns[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.80mL

0.56mL

0.28mL

14.00mL

2.80mL

1.40mL

28.00mL

5.60mL

2.80mL
参考文献

[1]Strydom SJ, et al. Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity. Nanomedicine. 2013;9(1):85-93.

[2]Munhoz DR, et al. Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing. Int J Biol Macromol. 2019;141:504-510.