MRT67307 HCl

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Chemical Structure| 2095432-39-4 同义名 : MRT67307 hydrochloride
CAS号 : 2095432-39-4
货号 : A248901
分子式 : C26H37ClN6O2
纯度 : 98+%
分子量 : 501.06
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 MRT67307 Hydrochloride is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.00mL

0.40mL

0.20mL

9.98mL

2.00mL

1.00mL

19.96mL

3.99mL

2.00mL
参考文献

[1]Clark K, MacKenzie KF, et al. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16986-91.

[2]Clark K, Peggie M, et al. Novel cross-talk within the IKK family controls innate immunity. Biochem J. 2011 Feb 15;434(1):93-104.