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Methyl gypsogenin-3-O-glucuronide

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Chemical Structure| 96553-02-5 同义名 : Gypsogenin-3-O-(6-O-methyl)-glucoside
CAS号 : 96553-02-5
货号 : A245062
分子式 : C37H56O10
纯度 : 99%
分子量 : 660.835
MDL号 : -
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(158.89 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Gypsogenin 3-O-beta-D-glucuronopyranoside, a natural product isolated and purified from the seeds of Momordica cochinchinensis, shows inhibitory activity toward pancreatic lipase with IC50 value of 0.29 mM, and the free carboxylic acid groups in position 28 within its chemical structures are required for enhancement of pancreatic lipase inhibition.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.51mL

0.30mL

0.15mL

7.57mL

1.51mL

0.76mL

15.13mL

3.03mL

1.51mL
参考文献

[1]Li F, Li W, et al. Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus. Chem Pharm Bull (Tokyo). 2007 Jul;55(7):1087-9.