产品说明书

Fenoprofen

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Chemical Structure| 29679-58-1 同义名 : LILLY-53858
CAS号 : 29679-58-1
货号 : A244887
分子式 : C15H14O3
纯度 : 98%
分子量 : 242.27
MDL号 : MFCD00072027
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(433.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 enoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to alleviate symptoms associated with arthritis, including osteoarthritis and rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain. Additionally, Fenoprofen acts as an allosteric enhancer of melanocortin receptors and promotes ERK1/2 activation[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.13mL

0.83mL

0.41mL

20.64mL

4.13mL

2.06mL

41.28mL

8.26mL

4.13mL
参考文献

[1]Tahereh Rezaei, et al. A universal methodology for reliable predicting the non-steroidal anti-inflammatory drug solubility in supercritical carbon dioxide. Sci Rep. 2022 Jan 20;12(1):1043.

[2]Xiao-Chen Yuan, et al. Fenoprofen-An Old Drug Rediscovered as a Biased Allosteric Enhancer for Melanocortin Receptors. ACS Chem Neurosci. 2019 Mar 20;10(3):1066-1074.