产品说明书
SR-1078
 |
同义名 : | - |
| CAS号 : | 1246525-60-9 | |
| 货号 : | A244776 | |
| 分子式 : | C17H10F9NO2 | |
| 纯度 : | 98+% | |
| 分子量 : | 431.252 | |
| MDL号 : | - | |
| 存储条件： |
粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 35 mg/mL(81.16 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SR1078 is a selective agonist of the retinoic acid receptor-related orphan receptors α and γ (RORα/RORγ). It binds directly to the ligand-binding domain of RORα and RORγ, enhancing their transcriptional activity and thereby stimulating the transcription of RORα/γ target genes[1][2]. | ||
| 作用机制 | SR1078 plays its role by directly binding to the ligand binding domain of RORα and RORγ and increases the transcriptional activity of these receptors, leading to stimulation of RORα/γ target gene transcription. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.32mL 0.46mL 0.23mL |
11.59mL 2.32mL 1.16mL |
23.19mL 4.64mL 2.32mL |
| 参考文献 |
|---|