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Protein kinase inhibitor H-7 2HCl

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Chemical Structure| 108930-17-2 同义名 : H-7 dihydrochloride;H-7 (hydrochloride);Protein kinase inhibitor H-7 dihydrochloride
CAS号 : 108930-17-2
货号 : A238262
分子式 : C14H19Cl2N3O2S
纯度 : 99%+
分子量 : 364.291
MDL号 : MFCD00036961
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 16 mg/mL(43.92 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Protein kinase inhibitor H-7 2HCl, a strong inhibitor of PKC, effectively halts the activity of both TPA (12-O-tetradecanoylphorbol-13-acetate, a skin tumor promoter) and phospholipase C-induced ornithine decarboxylase (ODC) at a concentration of 100 μM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.75mL

0.55mL

0.27mL

13.73mL

2.75mL

1.37mL

27.45mL

5.49mL

2.75mL
参考文献

[1]Fischer SM, et al. Mediation of phorbol ester-induced oxidant generation in murine epidermal cells by protein kinase C. Toxicol In Vitro. 1989;3(3):195-9.