产品说明书

7-Epi 10-desacetyl paclitaxel

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Chemical Structure| 78454-17-8 同义名 : 7-表-10-去乙酰基云南紫杉宁A ;7-epi-10-deacetyltaxol;10-Deacetyl-7-epipaclitaxel;Ormosin VI;7-epi-10-deacetyl Paclitaxel;10-Desacetyl-7-epipaclitaxel;10-Desacetyl-7-epi-taxol;10-Deacetyl-7-epitaxol
CAS号 : 78454-17-8
货号 : A237538
分子式 : C45H49NO13
纯度 : 98%
分子量 : 811.87
MDL号 : MFCD07779154
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(129.33 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 7-Epi 10-desacetyl paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.23mL

0.25mL

0.12mL

6.16mL

1.23mL

0.62mL

12.32mL

2.46mL

1.23mL
参考文献

[1]Swindell CS, Krauss NE, et al. Biologically active taxol analogues with deleted A-ring side chain substituents and variable C-2' configurations. J Med Chem. 1991 Mar;34(3):1176-84.

[2]Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by taxol. Nature. 1979 Feb 22;277(5698):665-7.