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Vitamin K4

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Chemical Structure| 573-20-6 同义名 : Acetomenaphthone;Menadiol diacetate;Vitamin K diacetate;NSC 403062;Kapilin
CAS号 : 573-20-6
货号 : A235488
分子式 : C15H14O4
纯度 : 98%
分子量 : 258.269
MDL号 : MFCD00021469
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(406.55 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Vitamin K4, a synthetic form of Vitamin K, is crucial for normal blood coagulation processes. It has the potential to halt cell cycle progression in the S phase and trigger apoptosis, making it a subject of interest in cancer research, particularly for prostate cancer and osteosarcoma[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.87mL

0.77mL

0.39mL

19.36mL

3.87mL

1.94mL

38.72mL

7.74mL

3.87mL

参考文献

[1]Jiang Y, et al. Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway. Pharmazie. 2013 Jun;68(6):442-8.

[2]Di W, et al. Vitamin K4 inhibits the proliferation and induces apoptosis of U2OS osteosarcoma cells via mitochondrial dysfunction. Mol Med Rep. 2017 Jan;15(1):277-284.