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Linoleic acid

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Chemical Structure| 60-33-3 同义名 : α-亚油酸 ;Octadecadienoic acid (all cis-9,12);C18:2 (all cis-9,12) Fatty acid
CAS号 : 60-33-3
货号 : A232282
分子式 : C18H32O2
纯度 : 99%
分子量 : 280.445
MDL号 : MFCD00064241
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(374.4 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

0.1 M NaOH: 8 mg/mL(28.53 mM),配合低频超声,水浴加热至45℃,并调节pH至11

动物实验配方:
生物活性
描述 Linoleic acid is an essential fatty acid of most vegetable oils and animal fats, and a prostaglandin precursor.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01603719 Infections St... 展开 >>ool Flora Stool Biochemistry Constipation Food Intolerance 收起 << Not Applicable Active, not recruiting December 2018 Germany ... 展开 >> Evangelisches Waldkrankenhaus Spandau Berlin, Germany, 13589 收起 <<
NCT02211612 Obesity Overf... 展开 >>eeding Muscle Mass Body Composition Ectopic Fat 收起 << Not Applicable Completed - Sweden ... 展开 >> Uppsala University; Clinical nutrition and metabolism; Dept of public health and caring sciences Uppsala, Please Select, Sweden, 75185 收起 <<
NCT03029572 Obesity Baria... 展开 >>tric Surgery Candidate 收起 << Not Applicable Completed - Switzerland ... 展开 >> University Hospitals of Geneva Geneva, Switzerland, 1206 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.57mL

0.71mL

0.36mL

17.83mL

3.57mL

1.78mL

35.66mL

7.13mL

3.57mL

参考文献

[1]Jandacek RJ. Linoleic Acid: A Nutritional Quandary. Healthcare (Basel). 2017 May 20;5(2). pii: E25.

[2]Knez M, Stangoulis JCR, et al. An initial evaluation of newly proposed biomarker of zinc status in humans - linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio. Clin Nutr ESPEN. 2016 Oct;15:85-92.