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Coclaurine

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Chemical Structure| 486-39-5 同义名 : (–)-Coclaurine;(S)-Coclaurine;(S)-Coclaurine, (–)-Coclaurine;Machiline
CAS号 : 486-39-5
货号 : A232032
分子式 : C17H19NO3
纯度 : 98%
分子量 : 285.34
MDL号 : MFCD19707510
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Coclaurine, a natural product isolated and purified from the root of Coptis chinensis Franch, blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.50mL

0.70mL

0.35mL

17.52mL

3.50mL

1.75mL

35.05mL

7.01mL

3.50mL
参考文献

[1]Choi KB, Morishige T, Sato F. Purification and characterization of coclaurine N-methyltransferase from cultured Coptis japonica cells. Phytochemistry. 2001 Apr;56(7):649-55.

[2]Watanabe H, Watanabe K, Kikuchi T. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6.