Mandelic acid

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Chemical Structure| 90-64-2 同义名 : 2-羟基-2-苯基乙酸 ;DL-Mandelic acid;(±)-Mandelic acid;DL-Amygdalic Acid
CAS号 : 90-64-2
货号 : A228156
分子式 : C8H8O3
纯度 : 98%
分子量 : 152.147
MDL号 : MFCD00064250
存储条件：

Pure form Keep in dark place,Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(690.12 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 2-Hydroxy-2-phenylacetic acid is an endogenous metabolite. 2-phenylacetic acid is a plant hormone in the endogenous auxin family[1]. The fluorescent bioassay is able to detect 4-hydroxyphenylacetic acid (4-HPA) and 2-phenylacetic acid (PAA) concentrations from 60 μM to 3 mM in a dose-responsive manner. The pyocyanin producing bioassay can detect 4-HPA concentrations from 1.9 to 15.625 μM and PAA concentrations from 15.625 to 125 μM, both in a dose-responsive manner[2]. Nematic liquid crystals (NLCs) form helical macroscopic structures through chiral induction when doped with chiral species. Using the standard NLC 4-cyano-4'-pentylbiphenyl (5CB), weakly doped with the chiral material 2-hydroxy-2-phenylacetic acid (mandelic acid)[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.57mL

1.31mL

0.66mL

32.86mL

6.57mL

3.29mL

65.73mL

13.15mL

6.57mL
参考文献

[1]{Guo KH, Lu KH, Yeh YC. Cell-Based Biosensor with Dual Signal Outputs for Simultaneous Quantification of Phenylacetic Acid and Phenylethylamine. ACS Synth Biol. 2018;7(12):2790‐2795

[2]Dierckx S, Van Puyvelde S, Venken L, Eberle W, Vanderleyden J. Design and Construction of a Whole Cell Bacterial 4-Hydroxyphenylacetic Acid and 2-Phenylacetic Acid Bioassay. Front Bioeng Biotechnol. 2015;3:88. Published 2015 Jun 16

[3]Rudquist P, Dietrich CF, Mark AG, Giesselmann F. Chirality Detection Using Nematic Liquid Crystal Droplets on Anisotropic Surfaces. Langmuir. 2016;32(24):6140‐6147