产品说明书

FSEN1

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Chemical Structure| 862808-01-3 同义名 : -
CAS号 : 862808-01-3
货号 : A2226501
分子式 : C22H22BrN5OS
纯度 : 98%
分子量 : 484.412
MDL号 : -
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 4 mg/mL(8.26 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

DMF: 1 mg/mL(2.06 mM)
动物实验配方：
生物活性
描述 FSEN1, a strong and selective inhibitor of FSP1 with an IC50 of 313 nM, promotes ferroptosis in cancer cells by blocking FSP1 and is researched for cancer treatment applications[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.06mL

0.41mL

0.21mL

10.32mL

2.06mL

1.03mL

20.64mL

4.13mL

2.06mL
参考文献

[1]Hendricks JM, et, al. Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Cell Chem Biol. 2023 May 4:S2451-9456(23)00114-9.