产品说明书
Xylitol
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同义名 : | Xylite;Adonitol;Adonite;D-Xylitol;Ribitol |
| CAS号 : | 87-99-0 | |
| 货号 : | A221974 | |
| 分子式 : | C5H12O5 | |
| 纯度 : | 98+% | |
| 分子量 : | 152.146 | |
| MDL号 : | MFCD00064292 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 125 mg/mL(821.58 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(657.26 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Xylitol, a substitute for sugar, is often used as a food additive [1-2] . In vitro studies, 25% xylitol, used in conjunction with 0.5 parts/10(6) respectively fluoride, could significantly decrease the mineral loss in freshly extracted bovine incisors, with the treatment of pure orange juice [3] . Besides this, it was also found that xylitol could inhibit the reproduction of oral bacteria, through depleting the cell or poisoning the glycolytic system [4] . In vivo studies, xylitol has the ability of changing gut microbiota but not lipid metabolism in mice, when given 40 and 194 mg/kg body weight/day in the diet [1] . In addition, it was observed that xylitol, used with red ginseng (RG), could improve the symptoms of influenza virus infection in mice [2] . | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02569697 | HIV | Phase 1 | Completed | - | United States, Virginia ... 展开 >> Eastern Virginia Medical School Norfolk, Virginia, United States, 23507 收起 << |
| NCT03578900 | Xerostomia Hy... 展开 >>posalivation Quality of Life Sjogren's Syndrome 收起 << | Phase 4 | Completed | - | - |
| NCT03625310 | Early Childhood Caries | Not Applicable | Completed | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.57mL 1.31mL 0.66mL |
32.86mL 6.57mL 3.29mL |
65.72mL 13.14mL 6.57mL |
| 参考文献 |
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