产品说明书

Aurantio-obtusin

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Chemical Structure| 67979-25-3 同义名 : -
CAS号 : 67979-25-3
货号 : A221042
分子式 : C17H14O7
纯度 : 99%+
分子量 : 330.289
MDL号 : MFCD13194886
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(75.69 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 GlucoAurantio-obtusin, a natural product isolated and purified from the seeds of Cassia obtusifolia L., possesses hypotensive and hypolipidemic effects.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.03mL

0.61mL

0.30mL

15.14mL

3.03mL

1.51mL

30.28mL

6.06mL

3.03mL
参考文献

[1]Yu J, Han JC, Gao YJ. Biotransformation of glucoaurantio-obtusin towards aurantio-obtusin increases the toxicity of irinotecan through increased inhibition towards SN-38 glucuronidation. Phytother Res. 2014 Oct;28(10):1577-80.

[2]Mi BL, Sun Q, et al. Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences. Xenobiotica. 2014 Aug;44(8):716-21.