Dalbergioidin

产品说明书

Print
Chemical Structure| 30368-42-4 同义名 : -
CAS号 : 30368-42-4
货号 : A219725
分子式 : C15H12O6
纯度 : 98+%
分子量 : 288.252
MDL号 : MFCD00238717
存储条件：

Pure form Inert atmosphere,Store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Dalbergioidin, a natural product isolated and purified from the roots of Parochetus communis with tyrosinase inhibitory activity with an IC50 of 20 mM, shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism, protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, and ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.47mL

0.69mL

0.35mL

17.35mL

3.47mL

1.73mL

34.69mL

6.94mL

3.47mL
参考文献

[1]Ren X, Bo Y, et al. Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF-β Signal Pathway. Mediators Inflamm. 2016;2016:5147571.

[2]Baek S, Kim J, et al. Inhibitory effect of dalbergioidin isolated from the trunk of Lespedeza cyrtobotrya on melanin biosynthesis. J Microbiol Biotechnol. 2008 May;18(5):874-9.