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H-Glu-OH

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Chemical Structure| 56-86-0 同义名 : 谷氨酸 ;(S)-Glutamic acid
CAS号 : 56-86-0
货号 : A211917
分子式 : C5H9NO4
纯度 : 98%
分子量 : 147.129
MDL号 : MFCD00002634
存储条件:

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 6 mg/mL(40.78 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors. L-Glutamic acid may act through metabotropic receptors in the ovaries to inhibit spawning, as l-(+)-2-amino-4-phosphonobutyric acid, an agonist for metabotropic glutamate receptors, also inhibited spawning induced by 1-MeAde[1]. L-Glu and L-Cys (l-glutamic acid (l-Glu) and L-cysteine (L-Cys) were able to prevent CPF-induced (organophosphorus insecticide chlorpyrifos) oxidative stress. The above-mentioned amino acids, administered alone and in their combination, can mitigate and suppress CPF-induced oxidative stress. The most significant mitigation effect was found in rats treated with L-Glu only[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.80mL

1.36mL

0.68mL

33.98mL

6.80mL

3.40mL

67.97mL

13.59mL

6.80mL

参考文献

[1]Mita M. Inhibitory mechanism of l-glutamic acid on spawning of the starfish Patiria (Asterina) pectinifera. Mol Reprod Dev. 2017;84(3):246-256

[2]Salyha N, Salyha Y. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018;64:155-163