产品说明书

Palvanil

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Chemical Structure| 69693-13-6 同义名 : -
CAS号 : 69693-13-6
货号 : A211744
分子式 : C24H41NO3
纯度 : 97%
分子量 : 391.587
MDL号 : N/A
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Palvanil, a Capsaicin analogue, exhibits potent TRPV1 receptor desensitization, resulting in anti-nociceptive and anti-inflammatory effects [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.55mL

0.51mL

0.26mL

12.77mL

2.55mL

1.28mL

25.54mL

5.11mL

2.55mL
参考文献

[1]Luciano De Petrocellis, et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. Pharmacol Res. 2011 Apr;63(4):294-9.

[2]Livio Luongo, et al. Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. Pharmacol Res. 2012 Sep;66(3):243-50.