Withaferin A
产品说明书
 |
同义名 : | NSC 101088;WFA;NSC 273757;WA |
| CAS号 : | 5119-48-2 | |
| 货号 : | A199705 | |
| 分子式 : | C28H38O6 | |
| 纯度 : | 98% | |
| 分子量 : | 470.598 | |
| MDL号 : | MFCD10687098 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 50 mg/mL(106.25 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Withaferin A is a steroidal lactone that is isolated from the plant Withania somnifera. It has potent anti-inflammatory properties as it inhibits the activation of NF-κ B signaling pathway. The anti-tumor activity of Withaferin A is due to its ability to alter cytoskeletal architecture by binding annexin II and disrupting F actin cross-links. Withaferin A also inhibits angiogenesis by binding to vimentin and F-actin. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.12mL 0.42mL 0.21mL |
10.62mL 2.12mL 1.06mL |
21.25mL 4.25mL 2.12mL |
