产品说明书
(-)-Pinoresinol
 |
同义名 : | - |
| CAS号 : | 81446-29-9 | |
| 货号 : | A198061 | |
| 分子式 : | C20H22O6 | |
| 纯度 : | 99+% | |
| 分子量 : | 358.385 | |
| MDL号 : | - | |
| 存储条件： |
粉末 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | (-)-Pinoresinol, a natural product isolated and purified from the bark of Eucommia ulmoides, can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. (-)-Pinoresinol also possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans. (-)-Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, which can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, suggests that this could be a mechanism by which PIN reduces proliferation and induces differentiation on HL60 cells. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.79mL 0.56mL 0.28mL |
13.95mL 2.79mL 1.40mL |
27.90mL 5.58mL 2.79mL |
| 参考文献 |
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