产品说明书

ML-097

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Chemical Structure| 743456-83-9 同义名 : CID-2160985
CAS号 : 743456-83-9
货号 : A197493
分子式 : C14H11BrO3
纯度 : 99%+
分子量 : 307.139
MDL号 : MFCD05264057
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(341.86 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 ML-097 , also known as CID-2160985, is a pan-Ras-associated GTPases activator that activates Rac1, cell division cycle 42, Ras, and Rab7[1].ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild-type, Ras protein wild-type, GTP-binding protein (Rab7), Rac1 protein-activating mutant, Rac1 protein wild-type, and Ras protein-activated mutant with EC50 values of 50.11 nM, 102.32 nM, and 109.64 nM, respectively, 20.41 nM, 81.28 nM, 151.35 nM and 93.32 nM, respectively[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.26mL

0.65mL

0.33mL

16.28mL

3.26mL

1.63mL

32.56mL

6.51mL

3.26mL
参考文献

[1]Zurab Surviladze, et al. Three small molecule pan activator families of Ras-related GTPases.