PFKFB3-IN-2

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Chemical Structure| 794552-84-4 同义名 : -
CAS号 : 794552-84-4
货号 : A1964100
分子式 : C14H11NO7S
纯度 : 99%
分子量 : 337.305
MDL号 : MFCD06591019
存储条件:

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 120 mg/mL(355.76 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 PFKFB3-IN-2, an inhibitor targeting 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3), is recognized for its potential in addressing cancer, neurodegenerative, autoimmune, inflammatory conditions, multiple sclerosis, metabolic disorders, and angiogenesis inhibition among other diseases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.96mL

0.59mL

0.30mL

14.82mL

2.96mL

1.48mL

29.65mL

5.93mL

2.96mL

参考文献

[1]Fedichev P, et al. Pfkfb3 inhibitors and their uses. World Intellectual Property Organization. WO2020080979.