产品说明书

Umbelliferone

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Chemical Structure| 93-35-6 同义名 : 7-Hydroxycoumarin;Hydrangin;7-Hydroxycoumarin, 7 Hydroxycoumarin, 7Hydroxycoumarin, Hydrangin, Skimmetin, Umbelliferone;beta-umbelliferone;skimmetine;hydrangine;NSC 19790
CAS号 : 93-35-6
货号 : A193753
分子式 : C9H6O3
纯度 : 98%
分子量 : 162.142
MDL号 : MFCD00006878
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 15 mg/mL(92.51 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

IP 2% DMSO+2% Tween80+30% PEG300+water 6 mg/mL clear

PO 0.5% CMC-Na 35 mg/mL suspension

生物活性
描述 Umbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., exhibits significant anticancer effects via the induction of apoptosis, cell cycle arrest and DNA fragmentation in HepG2 cancer cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.17mL

1.23mL

0.62mL

30.84mL

6.17mL

3.08mL

61.67mL

12.33mL

6.17mL

参考文献

[1]Yu SM, Hu DH, Zhang JJ. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-73.

[2]Rauf A, Khan R, et al. In vivo antinociceptive and anti-inflammatory activities of umbelliferone isolated from Potentilla evestita. Nat Prod Res. 2014;28(17):1371-4.