ISRIB
产品说明书
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同义名 : | - |
| CAS号 : | 548470-11-7 | |
| 货号 : | A193697 | |
| 分子式 : | C22H24Cl2N2O4 | |
| 纯度 : | 98% | |
| 分子量 : | 451.343 | |
| MDL号 : | MFCD27952932 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 7 mg/mL(15.51 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
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| 靶点 |
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| 描述 | ISRIB cis-Isomer is one of the isosteromers of ISRIB, which showed effect on inhibition of the ATF4 luciferase reporter in HEK293T cells treated with 2 µg/ml of tunicamycin to induce ER stress with IC50 value of 600nM[1]. Its isosteromer, ISRIB trans-Isomer, is the usual one used in research. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.22mL 0.44mL 0.22mL |
11.08mL 2.22mL 1.11mL |
22.16mL 4.43mL 2.22mL |
