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CB2R/FAAH modulator-2

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Chemical Structure| 2876918-68-0 同义名 : -
CAS号 : 2876918-68-0
货号 : A1929259
分子式 : C24H33NO2
纯度 : 99%+
分子量 : 367.524
MDL号 : N/A
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 CB2R/FAAH modulator-2 is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. CB2R/FAAH modulator-2 possesses Ki values of 10.8 nM and 152.9 nM for CB2R and CB1R, respectively, and an IC50 value of 6.2 μM for FAAH. CB2R/FAAH modulator-2 holds potential for use in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.72mL

0.54mL

0.27mL

13.60mL

2.72mL

1.36mL

27.21mL

5.44mL

2.72mL

参考文献

[1]Francesca Intranuovo, et al. Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. J Med Chem. 2023 Jan 12;66(1):235-250.