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Harmine hydrochloride

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Chemical Structure| 343-27-1 同义名 : 盐酸去氢骆驼蓬碱 ;Telepathine hydrochloride
CAS号 : 343-27-1
货号 : A189417
分子式 : C13H13ClN2O
纯度 : 97%
分子量 : 248.708
MDL号 : MFCD00012641
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 4 mg/mL(16.08 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 10 mg/mL(40.21 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方：
生物活性
描述 Harmine hydrochloride, a natural product isolated and purified from the herbs of Peganum harmala L., has potent anti-cancer effects in glioblastoma cells, which is at least partially via inhibition of Akt phosphorylation.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.02mL

0.80mL

0.40mL

20.10mL

4.02mL

2.01mL

40.21mL

8.04mL

4.02mL
参考文献

[1]Liu H, Han D, et al. Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma. J Neurooncol. 2013 Mar;112(1):39-48.