产品说明书

Bexagliflozin

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Chemical Structure| 1118567-05-7 同义名 : EGT-1442;THR-1442;EGT-0001442
CAS号 : 1118567-05-7
货号 : A187149
分子式 : C24H29ClO7
纯度 : 99%+
分子量 : 464.936
MDL号 : MFCD28100944
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.15mL

0.43mL

0.22mL

10.75mL

2.15mL

1.08mL

21.51mL

4.30mL

2.15mL
参考文献

[1]Zhang W, Welihinda A, et al. EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacol Res. 2011 Apr;63(4):284-93.