α-Glucosidase-IN-22

产品说明书

Print
Chemical Structure| 2870693-28-8 同义名 : -
CAS号 : 2870693-28-8
货号 : A1868788
分子式 : C14H11N3O2S
纯度 : 99%+
分子量 : 285.321
MDL号 : N/A
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(420.58 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 α-Glucosidase-IN-22, characterized as a benzimidazole compound, displays potent inhibition against α-glucosidase with an IC50 of 0.64 μM. It functions as a potent anti-diabetic agent and holds promise for type 2 diabetes mellitus (T2DM) research [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.50mL

0.70mL

0.35mL

17.52mL

3.50mL

1.75mL

35.05mL

7.01mL

3.50mL
参考文献

[1]Sardar Ali, et al. Novel 5-(Arylideneamino)-1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479.