产品说明书

Levomefolic acid

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Chemical Structure| 31690-09-2 同义名 : L-5-甲基四氢叶酸 ;5-MTHF;LMSR;Bodyfolin;Levomefolate;Levomefolinic acid;Nutrifolin;Metafolin
CAS号 : 31690-09-2
货号 : A182922
分子式 : C20H25N7O6
纯度 : 98%
分子量 : 459.456
MDL号 : MFCD00870135
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 2 mg/mL(4.35 mM),配合低频超声,并水浴加热至45℃助溶

动物实验配方:
生物活性
描述 Levomefolic acid is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00400387 Abortion, Habitual Phase 3 Completed - Austria ... 展开 >> Kinderwunschinstitut Schenk Dobl, Austria, A-8143 Germany Martin-Luther-Universität Halle Wittenberg Halle/Saale, Sachsen-Anhalt, Germany, 06120 Universitätsfrauenklinik am Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden Dresden, Germany, 01307 Krankenhaus St. Elisabeth und St. Barbara, Klinik für Frauenheilkunde und Geburtshilfe Halle / Saale, Germany, 06110 Medizinische Hochschule Hannover, Abt. für Gynäkologie und Geburtshilfe Hannover, Germany, 30625 Frauenklinik Landshut Achdorf Landshut, Germany Universitätsklinikum Schleswig-Holstein Lübeck, Germany Klinikum der Universität München Großhadern, Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe Muenchen, Germany, 81377 Frauenklinik der Technischen Universität München, Klinikum rechts der Isa Muenchen, Germany, 81675 Praxis für medizinische Genetik Regensburg, Germany, 93047 Klinikum Stuttgart, Frauenklinik Stuttgart, Germany, 70374 Universitätsfrauenklinik Tübingen Tuebingen, Germany, 72076 收起 <<
NCT00468481 - Completed - -
NCT00468481 Neural Tube Defects ... 展开 >> Contraception Oral Contraceptives (OC) 收起 << Phase 3 Completed - United States, California ... 展开 >> Orange County Clinical Trials Anaheim, California, United States, 92801 Medical Center for Clinical Research San Diego, California, United States, 92108 United States, Maryland SNBL Clinical Pharmacology Center, Inc. Baltimore, Maryland, United States, 21201 United States, New York Columbia University Medical Center New York, New York, United States, 10032 United States, North Carolina AAIPharma, Inc. Morrisville, North Carolina, United States, 27560 Lyndhurst Gynecologic Associates Winston-Salem, North Carolina, United States, 27103 United States, South Carolina Coastal Carolina Research Center Mt. Pleasant, South Carolina, United States, 29464 United States, Tennessee New Orleans Center for Clinical Research Knoxville, Tennessee, United States, 37920 United States, Washington NorthWest Kinetics Tacoma, Washington, United States, 98418 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.18mL

0.44mL

0.22mL

10.88mL

2.18mL

1.09mL

21.76mL

4.35mL

2.18mL

参考文献

[1]Hirsch S, Miranda D, et al. Natural killer cell cytotoxicity is not regulated by folic acid in vitro. Nutrition. 2013 May;29(5):772-6.

[2]Liu Y, Green TJ, et al. Microencapsulation of L-5-methyltetrahydrofolic acid with ascorbate improves stability in baked bread products. J Agric Food Chem. 2013 Jan 9;61(1):247-54.