产品说明书
(-)-Blebbistatin
 |
同义名 : | (−)-布雷他汀 ;(S)-Blebbistatin;(S)-(-)-Blebbistatin;Blebbistatin;(–)-Blebbistatin |
| CAS号 : | 856925-71-8 | |
| 货号 : | A182285 | |
| 分子式 : | C18H16N2O2 | |
| 纯度 : | 99%+ | |
| 分子量 : | 292.332 | |
| MDL号 : | MFCD08460907 | |
| 存储条件： |
粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 9 mg/mL(30.79 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
2% DMSO+40% PEG 300+5% Tween 80+water 5 mg/mL |
| 生物活性 | |||
|---|---|---|---|
| 靶点 |
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| 描述 | (-)-Blebbistatin selectively inhibits the ATPase activity of non-muscle myosin II[1][2]. | ||
| 作用机制 | Blebbistatin blocked myosin II–dependent cell processes by blocking cell blebbing rapidly and reversibly as well as rapidly disrupted directed cell migration and cytokinesis in vertebrate cells. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.42mL 0.68mL 0.34mL |
17.10mL 3.42mL 1.71mL |
34.21mL 6.84mL 3.42mL |
