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Chelidamic acid

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Chemical Structure| 138-60-3 同义名 : 白屈氨酸水合物 ;Chelidamic acid hydrate
CAS号 : 138-60-3
货号 : A181222
分子式 : C7H5NO5
纯度 : 97%
分子量 : 183.118
MDL号 : MFCD00066478
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 9 mg/mL(49.15 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 1 mg/mL(5.46 mM),配合低频超声助溶

动物实验配方:
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.46mL

1.09mL

0.55mL

27.30mL

5.46mL

2.73mL

54.61mL

10.92mL

5.46mL

参考文献

[1]Searcey M, et al. Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anticancer Drug Des. 13(8):837-55.

[2]Espinet P, et al. Mesogenic palladium complexes with pincer ligands derived from dipicolinic acid. Inorg Chem. 2000 Aug, 7;39(16):3645-51.

[3]Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50.