Ethyl gallate

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Chemical Structure| 831-61-8 同义名 : 3,4,5-三羟基苯甲酸乙酯 ;Ethyl 3,4,5-trihydroxybenzoate;Phyllemblin;NSC 402626;Gallic Acid;gallic acid ethyl ester
CAS号 : 831-61-8
货号 : A180539
分子式 : C9H10O5
纯度 : 98%
分子量 : 198.173
MDL号 : MFCD00016430
存储条件:

Pure form Inert atmosphere,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(529.84 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Ethyl gallate is a natural product isolated and purifeid from the herbs of Coriaria nepalensis, and it can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.05mL

1.01mL

0.50mL

25.23mL

5.05mL

2.52mL

50.46mL

10.09mL

5.05mL

参考文献

[1]Cui H, Yuan J, et al. Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-κB signaling. Oncol Rep. 2015 Mar;33(3):1284-90.

[2]Mink SN, Jacobs H, et al. Ethyl gallate, a scavenger of hydrogen peroxide that inhibits lysozyme-induced hydrogen peroxide signaling in vitro, reverses hypotension in canine septic shock. J Appl Physiol (1985). 2011 Feb;110(2):359-74.