产品说明书

	同义名 :	伊班膦酸
	CAS号 :	114084-78-5
	货号 :	A178979
	分子式 :	C9H23NO7P2
	纯度 :	98+%
	分子量 :	319.229
	MDL号 :	MFCD00868772
	存储条件：	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

临床研究
NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00091832	Breast Cancer ... 展开 >> Metastases Bone Metastases in Subjects With Advanced Breast Cancer 收起 <<	Phase 2	Completed	-	-
NCT00091832	-		Completed	-	-
NCT00873808	-		Withdrawn(lack of accrual)	-	United States, Washington ... 展开 >> University Cancer Center at University of Washington Medical Center Seattle, Washington, United States, 98195-6043 收起 <<

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	3.13mL 0.63mL 0.31mL	15.66mL 3.13mL 1.57mL	31.33mL 6.27mL 3.13mL

参考文献
[1]Epplen R, Stockle M, et al. Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. Acta Oncol. 2011 Jan;50(1):127-33. [2]Morgan C, Jeremiah S, et al. Metronomic administration of ibandronate and its anti-angiogenic effects in vitro. Microvasc Res. 2009 Dec;78(3):453-8.