产品说明书
Sulfadimethoxine
 |
同义名 : | 磺胺二甲氧嗪 ;Sulphadimethoxine |
| CAS号 : | 122-11-2 | |
| 货号 : | A178691 | |
| 分子式 : | C12H14N4O4S | |
| 纯度 : | 98+% | |
| 分子量 : | 310.329 | |
| MDL号 : | MFCD00057345 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(338.35 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
IP 5% DMSO+30% PEG400+ 2% tween80 + 63% water 3 mg/mL clear |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Sulfadimethoxine (SDM) is an antibiotic often used in combination with ormetoprim to prevent the spread of disease in freshwater aquaculture[1]. At antibiotic concentrations between 5 and 7 mg/L, SDM inhibited the growth of anammox bacteria and resulted in a decrease of Candidatus Brocadia abundance from 2.57% to 0.39%[2]. The excess sulfadimethoxine (SDM) in the environment could lead to antibiotic resistance by microorganisms and may do harm to many aquatic organisms. H2PO4- improved the efficiency of SDM removal by KMnO4. Humic acid (0-10 mg L-1) promoted the removal of SDM, which was attributed to the generation of in situ MnO2[3]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00770250 | - | Completed | - | - | |
| NCT00695838 | - | Completed | - | - | |
| NCT00882128 | - | Completed | - | - | |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.22mL 0.64mL 0.32mL |
16.11mL 3.22mL 1.61mL |
32.22mL 6.44mL 3.22mL |
| 参考文献 |
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