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(-)-Indolactam V

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Chemical Structure| 90365-57-4 同义名 : Indolactam V;(−)-Indolactam V;(-)-ILV
CAS号 : 90365-57-4
货号 : A178399
分子式 : C17H23N3O2
纯度 : 98+%
分子量 : 301.383
MDL号 : MFCD00151197
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(165.9 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 (-)-Indolactam V is a protein kinase C activator, which strongly directs human ES cell-derived definitive endoderm into pancreatic endoderm.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.32mL

0.66mL

0.33mL

16.59mL

3.32mL

1.66mL

33.18mL

6.64mL

3.32mL

参考文献

[1]Ongley SE, Bian X, et al. High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium. ACS Chem Biol. 2013 Sep 20;8(9):1888-93.

[2]Thatava T, Nelson TJ, et al. Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny. Gene Ther. 2011 Mar;18(3):283-93.