产品说明书
Phytol
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同义名 : | 植醇 ;(E)-Phytol;trans-Phytol |
| CAS号 : | 150-86-7 | |
| 货号 : | A178143 | |
| 分子式 : | C20H40O | |
| 纯度 : | 95% | |
| 分子量 : | 296.531 | |
| MDL号 : | MFCD00151280 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 120 mg/mL(404.68 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 无水乙醇: 25 mg/mL(84.31 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Phytol is an acyclic monounsaturated diterpene alcohol generated from chlorophyll metabolism that exerts anti-inflammatory, antithrombotic, antimicrobial, and antitumor effects. In vitro, phytol suppressed α-melanocyte-stimulating hormone-induced melanogenesis in B16F10 murine melanoma cells without any toxic effects. Treatment with phytol inhibited the expression of microphthalmia-associated transcription factor (MITF) by phosphorylating extracellular signal-regulated protein kinase (ERK)[3]. Moreover, the important biometebolite of phytol is phytanic acid (PA). Evidence shows PA to have cytotoxic, anticancer, antidiabetic, lipid lowering and anti-teratogenic activities[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.37mL 0.67mL 0.34mL |
16.86mL 3.37mL 1.69mL |
33.72mL 6.74mL 3.37mL |
| 参考文献 |
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