产品说明书
Probucol
 |
同义名 : | DH-581;Lorelco;Hoechst Brand of Probucol;Superlipid;Lurselle;Lesterol;Bisphenabid;Biphenabid;NSC 652160;NSC 86225 |
| CAS号 : | 23288-49-5 | |
| 货号 : | A177844 | |
| 分子式 : | C31H48O2S2 | |
| 纯度 : | 98% | |
| 分子量 : | 516.842 | |
| MDL号 : | MFCD00079281 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(203.16 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
IP 2% DMSO+2% Tween80+30% PEG300+water 9 mg/mL clear PO 0.5% CMC-Na 39 mg/mL suspension |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Probucol is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT03753555 | Stroke, Ischemic ... 展开 >> Atherosclerosis, Cerebral 收起 << | Phase 4 | Not yet recruiting | November 30, 2021 | - |
| NCT00598533 | Coronary Heart Disease | Phase 4 | Completed | - | Germany ... 展开 >> Medizinische Klinik, Klinikum rechts der Isar Muenchen, Germany, 81675 Deutsches Herzzentrum Muenchen Munich, Germany, 80636 收起 << |
| NCT00276133 | Chronic Nephropathy | Phase 4 | Completed | - | Japan ... 展开 >> Yokohama City University Center Hospital Yokohama, Kanagawa, Japan, 232-0024 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.93mL 0.39mL 0.19mL |
9.67mL 1.93mL 0.97mL |
19.35mL 3.87mL 1.93mL |
| 参考文献 |
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